Endocrine Abstracts

Thyrotropin-secreting pituitary adenomas (TSHomas) are rare functioning pituitary adenomas, accounting for less than 1%. They commonly present as macroadenomas with symptoms of hyperthyroidism. Though surgery is the first line therapy, cure is achieved in only 30–40%, with high rate of post-surgical hypopituitarism. We propose somatostatin analogs having a new role in the management. We report a case of 73 years-old man with a 6-month history of palpitations and progress...

Introduction: Hypophysitis is a rare disease. Lately, it is more frequent due to the use of Inmune Check Point Inhibitor (ICPIs). Ipilimumab or combo Ipilimumab + Nivolumab are the main cause. Agree with literature, 17-18% of the patients with these drugs suffer from. By contrast, with Idiopatic Autoimmune Hypophysitis and Lymphocytic Hypophysitis, this type of hypophysitis occurs in sixties men. Autoinmunity mechanism is known, but precise pathophysiology is unclear <p cl...